It really depends on how familiar you are with css, and how willing you are to learn.
A layout like that is indeed custom, and while we;d be happy to help, it would be mostly in the form of pointing you towards tutorials.
These forums were CLOSED to new posts on November 19th, 2012. New forums are here: http://www.studiopress.com/forums/
and you will need to SIGN UP AGAIN.
If you need assitance with setting up your theme, go to http://my.studiopress.com/
and read the SETUP links or the TUTORIALS link on the side tab.
If you need Account Assistance
, file a help desk ticket at the same location.