regular post type VS custom post type for an art database.

[GB]

I am interested in building a web site using wordpress and genesis that is a database of over 20 years of artwork that spans many mediums and genres.

I gravitate towards the grid view layout to be able to see many thumbnails at a time.

The question is which is the better route to take:

A custom post type or regular post type?

I have been advised that a regular post type is better suited however I like the way this site works http://themes.themedizain.com/dizain-01/portfolio/

It however uses custom post types.

What is the opinion here of which is the best approach, custom post type or regular?

I am dealing with a huge database of work and want to make the right choice from the start.

Thanks...